TABLE 1.
Characteristics of patients with antibodies to alpha-gal presented
| IgE IU/mL | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pt. | Diagnosis | Age | Sex | Race | State | Tick bites | Blood type | sTryp ng/mL | Frequency events/year | Total | Alpha-gal | Alpha-gal / IgE ratio | Pork | Beef |
| 1 | IA/ISM | 61 | M | W | VA | Y | O− | 16.3 | 4 | 28.8 | 2.7 | 0.093 | 0.51 | 0.46 |
| 2 | IA/ISM | 70 | M | W | AL | Y | O− | 15.6 | 6 | 28.0 | 1.1 | 0.039 | 0.26 | 0.28 |
| 3 | IA | 55 | M | W | MO | Y | O+ | 3.3 | 6 | 82.6 | 18.8 | 0.227 | 3.0 | 4.5 |
| 4 | IA | 37 | M | W | TN | Y | O+ | 6.4 | 4 | 96.9 | 14.8 | 0.152 | 4.5 | 6.2 |
| 5 | IA | 50 | M | W | NJ | Y | O+ | 4.0 | 5 | 1284 | 218 | 0.169 | 22.3 | 37.5 |
| 6 | IA | 41 | M | W | VA | Y | A− | 4.1 | 12 | 71.2 | 0.36 | 0.005 | 0.10 | 0.10 |
sTryp, serum tryptase.
All patients with delayed anaphylaxis had IgE Ab specific to alpha-gal above 0.35 kUA/L and considered positive (lower limit of detection 0.1 IU/mL).