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. 2020 Apr 27;10(13):5671–5686. doi: 10.7150/thno.42539

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Elevated Mettl3/Snail level is associated with poor outcomes of HCC. (A) Mettl3 protein levels in 79 human liver cancer tissues were analyzed by immunohistochemistry. The images show different staining intensities of Mettl3 protein. Scale bars, 100 μm (upper panel), 25 μm (lower panel). (B-D) Kaplan-Meier survival curves of overall survival based on Mettl3 (B), Snail (C), or Mettl3 and Snail co-expression (D) in HCC patients. Log-rank analysis was employed to compare differences between any two groups.