Figure 3.

Representative in vivo biodistribution of FL-L1-S0456 in mouse xenografts. FaDu, MDA-MB231, KB, and HT29 bearing mice were intravenously injected with FL-L1-S0456 (10 nmoles) either in the presence (B; competition) or absence (A; Dye) of excess of the FL. Mice were euthanized 2 h post injection and biodistribution was performed. Organs and tissues were imaged using IVIVS Lumina. Images were acquired using the same imaging parameters across the tumor type and adjusted to same scale bar within each tumor type. List of organs (from top to bottom): Tumor, Heart, Lungs, Spleen, Pancreas, Muscle, Stomach, Small Intestine, Large Intestine, Liver, Kidney. N=5 for each group.