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. 2020 Apr 27;10(13):5790–5801. doi: 10.7150/thno.44789

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UBTD1 is down-regulated in HCC and correlates with patient survival. (A) Western blot analysis of UBTD1 levels in paired human HCC and matched adjacent non-tumorous tissues. (B) Representative images of IHC staining of UBTD1 in HCC and non-tumor tissues. (C) Overall survival rates of HCC patients in low-UBTD1 and high-UBTD1 groups. (D) Tumor growth curve revealed that UBTD1 overexpression significantly inhibited tumor growth in vivo. Tumor nodules were subjected to immunohistochemical staining for Ki-67 (E) and YAP (F). *P < 0.05.