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. 2020 May 16;10(14):6411–6429. doi: 10.7150/thno.42602

Figure 3.

Figure 3

Glutamine deprivation alters neuroblastoma radioresistant properties. (A, B) Radiobiological colony forming assay of (A) SH-SY5Y and (B) BE(2)-C cells upon 24 h glutamine deprivation (n ≥ 3; ± S.E.M; ***p < 0.001). (C, D) Radiobiological colony forming assay of BE(2)-C cells following MYCN downregulation (C) with glutamine or (D) upon 24 h glutamine deprivation (n ≥ 3; ± S.E.M; ns p > 0.05; **p < 0.01). (E, F) Radiobiological colony forming assay of BE(2)-C following c-MYC downregulation (E) with glutamine or (F) upon 24 h glutamine deprivation (n ≥ 3; ± S.E.M; ns p > 0.05). (G, H) Radiobiological colony forming assay of SH-SY5Y following c-MYC downregulation (G) with glutamine or (H) upon 24 h glutamine deprivation (n ≥ 3; ± S.E.M; ***p < 0.001).