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CDK12 knocking down inhibits tumor growth by blocking MAPK signaling pathway. A. Representative images and histogram of H&E and CDK12, Ki67, phospho-MEK, phospho-ERK IHC staining after formalin-fixed paraffin-embedded SNU-1 xenografts and PDXs tumors. Data represent means ±SD. P<0.05: *, p<0.01: **, p<0.001: ***. Significance determined by two-tailed Student's t test.
