Table 1.
Microglia markers in health and disease
| Microglia | Markers | References |
|---|---|---|
| Homeostatic | Cd11b+ | Hickman et al. (2013), Butovsky et al. (2014), Asai et al. (2015), Greenhalgh et al. (2016), Zrzavy et al. (2017) |
| Cd45low | ||
| Cx3cr1+ | ||
| F4/80+ | ||
| Fcrls+ | ||
| Iba1+ | ||
| Olfml3+ | ||
| P2ry12+ | ||
| Sall1+ | ||
| Siglec-H+ | ||
| Tmem119+ | ||
| Tgfbr+ | ||
| Csf1r+ | ||
| Neurodegenerative diseases | Arg1↑ | Chiu et al. (2013), Holtman et al. (2015), Keren-Shaul (2017), Krasemann (2017), Zrzavy et al. (2017) |
| Apoe ↑ | ||
| Axl ↑ | ||
| Ccl2 ↑ | ||
| Cd45 ↑ | ||
| Clec7a ↑ | ||
| Gpnmb ↑ | ||
| Msr1↑ | ||
| Spp1↑ | ||
| Cd11b → | ||
| F4/80 → | ||
| Fcrls → | ||
| Iba1 → | ||
| Tmem119 → | ||
| Csf1r↓ | ||
| P2ry12 ↓ | ||
| Siglec-H ↓ | ||
| Sall1 ↓ | ||
| Tgfbr↓ |
Arrows indicate changes in expression: ↑ increased, ↓ decreased, → unchanged