Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 1;9(1):1744947. doi: 10.1080/2162402X.2020.1744947

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 7. — Neoantigen load from SNM and INDEL predicts overall survival. (a) Overall survival of BRCA patients separated by low (bottom 25%), medium (middle 50%) and high (top 25%) class I SNM and INDEL neoantigen load. When corrected for immune filtration, tumor stage, breast cancer subtype, and age at diagnosis using the Cox proportional hazard models, low neoantigen load showed significantly worse survival than medium neoantigen load (p = .04). (b) Overall survival of BRCA patients separated by low (bottom 25%), medium (middle 50%) and high (top 25%) class II SNM and INDEL neoantigen load. When corrected for immune filtration, breast cancer subtype and age cohort using the Cox proportional hazard models, low neoantigen load showed significantly worse survival than medium neoantigen load (p = .042).