Fig. 1.

The flow chart and a simplified tree classification structure of CHEER. Order classifier: classify reads into orders O1 to O3. O1-O3: classifiers within O1, O2, and O3, which assign family-level labels within each order. F1-F7: classifiers within each family from F1 to F7, which assign genus-level labels within each family. Genera1-Genera7: a set of genera under each family level. The dash line under each classifier shows the early stop function. The highlighted path with orange color shows the top-down classification path for a read from genera 7. The highlighted path with yellow shows the top-down classification path that stops at the family level determined by the early stop function. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)