Table 3.
Combination of hematologic, biochemical and coagulate parameters in EJC prognosis
| Variables | Authors | Number of EJC Patients | Cutoff Values | Survival Types | Hazard Ratio | 95% Confidence Interval | P-Value |
|---|---|---|---|---|---|---|---|
| CONUT score | Kudou K49 | 59 | 3 | OS | 4.749 | 2.146-10.09 | a0.0003 |
| F-NLR | Cong X19 | 129 | 1 | OS | 1.921 | 1.124-3.283 | 0.017 |
| 2 | OS | 2.764 | 1.559-4.900 | 0.001 | |||
| Tianxing G56 | 129 | - | OS | 1.730 | 1.173-2.551 | 0.006 | |
| PNI | Han WX48 | 101 | 51 | OS | 0.751 | 0.372-1.518 | 0.426 |
| Noble F26 | 138 | 47.50 | OS | - | - | 0.323 | |
| DFS | 0.979 | 0.950-1.009 | 0.165 | ||||
| Urabe M59 | 112 | con | OS | 0.62 | 0.47-0.82 | <0.001 | |
| DFS | 0.60 | 0.46-0.78 | <0.001 | ||||
| Zhang L21 | 355 | 51.3 | OS | 1.192 | 0.828-1.715 | 0.345 | |
| AGR/PNI | Wang Y60 | 215 | 1/2 | OS | 0.613 | 0.226-0.923 | <0.001 |
EJC: esophagogastric junction cancer; CONUT score: controlling nutritional status score; F-NLR: combination of fibrinogen concentration and neutrophil-lymphocyte ratio; PNI: prognostic nutritional index; AGR: albumin-to-globulin ratio; OS: overall survival; DFS: disease-free survival; con: continuous variable
a statistical significance in univariate analysis