Exploring HOTAIR from the Cancer Genome Atlas (TCGA) in cancers by online tools “GEPIA”, “UALCAN” and “Survexpress”. A. The expression of lncRNA HOTAIR was analyzed by “UALCAN” and the data were from TCGA. The expression of lncRNA HOTAIR was upregulated in colon cancer tissue (n=286) and the paired normal colon tissue (n=41). B. The expression of lncRNA HOTAIR was further analyzed by “GEPIA”in different clinical stages and lncRNA HOTAIR was upregulated higher in stage IV and stage III than that in stage I and stage II. C. The expression of lncRNA HOTAIR in different nodal stages by“UALCAN”, and lncRNA HOTAIR was upregulated higher in N IV and stage III than that in stage I and stage II. D. The expression of lncRNA was upregulated in adenocarcinoma than normal tissue analyzed by “UALCAN”. E. and F. The high expression of LncRNA HOTAIR indicated the lower overall survival analyzed by “GEPIA”(E) and “Survexoress”(F) *, P<0.05. **, P<0.01. G. and H. The high expression of LncRNA HOTAIR suggested the lower disease free survival analyzed by “PrognoScan” *, P<0.05. **, P<0.01.