Table 2.

Univariate and multivariate analyses of clinicopathologic factors for OS in colorectal cancer patients

Variable	Univariate analysis				Multivariate analysis
	HR	95% CI	P value		HR	95% CI	P value
Age (≥60 vs. <60 years)	0.683	0.238∼3.175	0.758
Sex (Male vs. Female)	0.786	0.285∼2.233	0.657
Tumour diameter (≥5 vs. <5 cm)	0.866	0.365∼2.015	0.743
Depth of invasion (T1+T2 vs. T3+T4)	1.325	0.548∼6.224	0.344
MMR index (dMMR vs. pMMR)	1.169	0.163∼0.855	0.057
Histological differentiation (Poor vs. Well)	3.266	0.061∼0.706	0.135
Lymph node metastasis (N vs. P)	0.20	0.012∼0.219	0.001**		0.024	0.001∼0.686	0.029*
Distant metastasis (N vs. P)	1.625	2.537∼24.339	0.001**		6.560	3.299∼32.566	0.012*
HOTAIR expression (High vs. Low)	0.152	0.114∼0.562	0.012**		0.188	0.038∼0.757	0.017*

HR, hazard ratio; N, negative; P, positive; *P<0.05, **P<0.01.