Table 4.

KEGG pathway enrichment

Types	Description	Number	FDR
wt	positive regulation of GTPase activity	226	1.54E-09
wt	regulation of GTPase activity	240	2.30E-09
wt	positive regulation of cellular component organization	369	6.57E-09
wt	positive regulation of hydrolase activity	301	6.57E-09
wt	positive regulation of molecular function	547	6.57E-09
wt	regulation of hydrolase activity	409	1.09E-08
wt	positive regulation of catalytic activity	465	1.19E-07
wt	establishment of localization in cell	582	1.56E-07
wt	vesicle-mediated transport	426	2.35E-06
wt	intracellular transport	491	3.19E-06
int	Alcoholism	54	0
int	Systemic lupus erythematosus	46	0
int	Transcriptional misregulation in cancer	33	0.002252
co	ECM-receptor interaction	27	2.93E-05
co	HIF-1 signaling pathway	24	0.04264
co	Alcoholism	35	0.04264
co	Systemic lupus erythematosus	28	0.04264
co	Hematopoietic cell lineage	22	0.04264
co	Cholinergic synapse	24	0.04264
co	cAMP signaling pathway	37	0.04264
co	AGE-RAGE signaling pathway in diabetic complications	22	0.04264
co	Proteoglycans in cancer	37	0.04264
co	Focal adhesion	37	0.04264

wt: IDH-wildtype;

int: IDH-mutation 1p/19q intact;

co: IDH-mutation 1p/19q codeletion;

FDR: false discovery rate.