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CDK12 activates the c-myc/b-catenin pathway and may regulate cancer cell stemness (A): Western blotting was utilized to assess the relative expression of wnt-1, c-myc, CD44, β-catenin, slug and snail in TPC-1-sh-ctr and KAT-5-sh-CDK12 cells. Actin was used as the internal control. **, P<0.01; ***, P<0.001;****, P<0.0001.(B): the quantitative analysis of the Western blot, **, P<0.01; ***, P<0.001;****, P<0.0001.
