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. 2020 Apr 14;46(1):97–106. doi: 10.3892/ijmm.2020.4577

Figure 1.

Figure 1

Sevo could suppress the proliferation and invasion capabilities of hepatocellular carcinoma cells. HCCLM3 and Huh7 cells were treated with different concentrations (0, 1.7, 3.4, and 5.1%) of Sevo for 6 h. (A) Cell proliferation was determined by MTT assay. (B) Cytotoxicity was measured by LDH assays. (C) Quantification of the invading and migratory cells. (D) Transwell and wound healing assays were used to examine cell invasion and migration in HCCLM3 and Huh7 cells (magnification, ×200). Data are the mean ± standard deviation. (n=3) of three representative experiment, *P<0.01 and **P<0.01 vs. NC group. Sevo, sevoflurane; NC, negative control; LDH, lactate dehydrogenase; OD, optical density.