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. 2020 Apr 14;46(1):97–106. doi: 10.3892/ijmm.2020.4577

Figure 2.

Figure 2

Sevo downregulates the expression of miR-25-3p in hepatocellular carcinoma cells. (A) miRNA microarray analysis was performed to compare the miRNA expression profiles in HCCLM3 cells treated with or without Sevo. (B) HCCLM3 and Huh7 cells were treated with different concentrations (0, 1.7, 3.4, and 5.1%) of Sevo for 6 h and then the expression of miR-25-3p was measured by reverse transcription-quantitative polymerase chain reaction. Data are the mean ± standard deviation. (n=3) of three representative experiment, *P<0.01 and **P<0.01 vs. control group. Sevo, sevoflurane; miR/miRNA, microRNA.