Figure 4.
Aberrant methylation patterns of lncRNAs revealing different biological functions. Significantly enriched GO terms of (A) hypermethylated lncRNAs and (B) hypomethylated lncRNAs by co-expressed protein-coding genes. Significantly enriched KEGG pathways of (C) hypermethylated lncRNAs and (D) hypomethylated lncRNAs by co-expressed protein-coding genes. lncRNA, long non-coding RNA; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.

