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. 2020 Apr 8;46(1):211–223. doi: 10.3892/ijmm.2020.4570

Figure 9.

Figure 9

miR-346 inhibits the expression of LRP6 in trophoblast cells. (A-C) JEG-3 cells were transfected with inhibitor control, miR-346 inhibitor, inhibitor control + mock, and inhibitor + siLRP6; (D-F) HTR8/SVneo cells were transfected with mimics control, miR-346 mimics, mimics control + mock, and mimics + LRP6. Western blot and RT-qPCR analyses were performed to determine the expression level of LRP6 in the transfected cells. *P<0.05 vs. inhibitor control or mimics control; ##P<0.001 vs. inhibitor or mimics (n=3). LRP6, low-density-lipoprotein receptor-related protein 6.