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. 2020 Apr 24;46(1):67–82. doi: 10.3892/ijmm.2020.4589

Figure 5.

Figure 5

Juglanin impedes ROS generation via MAPK signaling pathway suppression. (A) Western blot analysis was applied to determine p-p38, p-ERK1/2, and p-JNK protein expression levels. (B) The p-p38, (C) p-ERK1/2, and (D) p-JNK expression levels were quantified according to the results of immunoblotting analysis. Data are presented as the mean ± standard error of the mean (n=8). ***P<0.001 vs. the Con group. +P<0.05, ++P<0.01 and +++P<0.001 vs. the UVB group. ROS, reactive oxygen species; MAPK, mitogen activated protein kinases; p, phosphorylated; ERK, extracellular signal-regulated kinase; JNK, c-Jun N-terminal kinases; Con, control; UVB, ultraviolet B.