Table 1:
Baseline Characteristics
| Total | % | White | % | Black | % | Hispanic | % | Asian/Indian | % | p-Value | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Age at Diagnosis (N) | 428 | 313 | 73.1 | 21 | 4.9 | 77 | 18.0 | 17 | 4.0 | 0.379 | |
| <50 | 102 | 23.8 | 74 | 23.6 | 7 | 33.3 | 15 | 19.5 | 6 | 35.3 | |
| ≥50 | 326 | 76.2 | 239 | 76.4 | 14 | 66.7 | 62 | 80.5 | 11 | 64.7 | |
| Gender (N) | 428 | 313 | 73.1 | 21 | 4.9 | 77 | 18.0 | 17 | 4.0 | 0.911 | |
| Male | 247 | 57.7 | 181 | 57.8 | 11 | 52.4 | 46 | 59.7 | 9 | 52.9 | |
| Female | 181 | 42.3 | 132 | 42.2 | 10 | 47.6 | 31 | 40.3 | 8 | 47.1 | |
| Marital Status (N) | 425 | 311 | 73.2 | 21 | 4.9 | 76 | 17.9 | 17 | 4.0 | 0.001 | |
| Married | 299 | 70.4 | 235 | 75.6 | 9 | 42.9 | 40 | 52.6 | 15 | 88.2 | |
| Unmarried | 126 | 29.6 | 76 | 24.4 | 12 | 57.1 | 36 | 47.4 | 2 | 11.8 | |
| KPS (N) | 428 | 313 | 73.1 | 21 | 4.9 | 77 | 18.0 | 17 | 4.0 | 0.459 | |
| ≥70 | 346 | 80.8 | 258 | 82.4 | 16 | 76.2 | 58 | 75.3 | 14 | 82.4 | |
| <70 | 82 | 19.2 | 55 | 17.6 | 5 | 23.8 | 19 | 24.7 | 3 | 17.6 | |
| Extent of Surgical Resection (N) | 302 | 217 | 71.9 | 16 | 5.3 | 57 | 18.9 | 12 | 4.0 | 0.411 | |
| Gross Total Resection | 193 | 63.9 | 139 | 64.1 | 13 | 81.3 | 32 | 56.1 | 9 | 75.0 | |
| Subtotal Resection | 45 | 14.9 | 29 | 13.4 | 2 | 12.5 | 13 | 22.8 | 1 | 8.9 | |
| Biopsy | 64 | 21.2 | 49 | 22.6 | 1 | 6.3 | 12 | 21.1 | 2 | 16.7 | |
| RPA Class (N) | 366 | 264 | 72.1 | 18 | 4.9 | 68 | 18.6 | 16 | 4.4 | 0.203 | |
| III | 38 | 10.4 | 30 | 11.4 | 1 | 5.6 | 5 | 7.4 | 2 | 12.5 | |
| IV | 224 | 61.2 | 163 | 44.5 | 15 | 4.1 | 36 | 52.9 | 10 | 62.5 | |
| V/VI | 104 | 28.4 | 71 | 26.9 | 2 | 11.1 | 27 | 39.7 | 4 | 25.0 | |
| RT Technique (N) | 421 | 308 | 73.2 | 20 | 4.8 | 76 | 18.1 | 17 | 4.0 | 0.001 | |
| IMRT | 231 | 54.9 | 169 | 54.9 | 12 | 60.0 | 38 | 50.0 | 12 | 70.6 | |
| 3D CRT | 170 | 40.4 | 133 | 43.2 | 7 | 35.0 | 26 | 34.2 | 4 | 23.5 | |
| 2D | 20 | 4.8 | 6 | 1.9 | 1 | 5.0 | 12 | 15.8 | 1 | 5.9 | |
| RT Total Dose (N) | 428 | 313 | 73.1 | 21 | 4.9 | 77 | 18.0 | 17 | 4.0 | 0.617 | |
| <36 Gy | 42 | 9.8 | 32 | 10.2 | 2 | 9.5 | 8 | 10.4 | 0 | 0 | |
| 36–54 Gy | 41 | 9.6 | 31 | 9.9 | 0 | 0 | 9 | 11.7 | 1 | 5.9 | |
| >54 Gy | 345 | 80.6 | 250 | 29.9 | 19 | 90.5 | 60 | 77.9 | 16 | 94.1 | |
| Laterality (N) | 399 | 290 | 72.7 | 20 | 5.0 | 73 | 18.3 | 16 | 4.0 | 0.973 | |
| Unilateral | 331 | 83.0 | 241 | 83.1 | 17 | 85.0 | 60 | 82.2 | 13 | 81.3 | |
| Bilateral | 68 | 17.0 | 49 | 16.9 | 3 | 15.0 | 13 | 17.8 | 3 | 18.8 | |
| Multicentricity (N) | 399 | 290 | 72.7 | 20 | 5.0 | 73 | 18.3 | 16 | 4.0 | 0.278 | |
| No | 314 | 78.7 | 222 | 76.6 | 17 | 85.0 | 63 | 86.3 | 12 | 75.0 | |
| Yes | 85 | 21.3 | 68 | 23.4 | 3 | 15.0 | 10 | 13.7 | 4 | 25.0 | |
| IDH-1 Status (N) | 93 | 68 | 73.1 | 3 | 3.2 | 16 | 17.2 | 6 | 6.5 | 0.406 | |
| Negative | 87 | 93.5 | 63 | 92.6 | 3 | 100 | 16 | 100 | 5 | 83.3 | |
| Positive | 6 | 6.5 | 5 | 7.4 | 0 | 0 | 0 | 0 | 1 | 16.7 | |
| MGMT Status (N) | 65 | 46 | 70.8 | 2 | 3.1 | 12 | 18.5 | 5 | 7.7 | 0.259 | |
| Unmethylated | 38 | 58.5 | 28 | 60.9 | 2 | 100 | 7 | 58.3 | 1 | 20.0 | |
| Methylated | 27 | 41.5 | 18 | 29.1 | 0 | 0 | 5 | 41.7 | 4 | 80.0 | |
| Temozolomide (N) | 286 | 208 | 72.7 | 15 | 5.2 | 51 | 17.8 | 12 | 4.2 | 0.216 | |
| Yes | 265 | 92.7 | 191 | 91.8 | 13 | 86.7 | 50 | 98.0 | 11 | 91.7 | |
| No | 21 | 7.3 | 17 | 18.2 | 2 | 13.3 | 1 | 2.0 | 1 | 8.3 |