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. Author manuscript; available in PMC: 2020 May 28.
Published in final edited form as: World Neurosurg. 2015 Dec 31;88:260–269. doi: 10.1016/j.wneu.2015.12.081

Table 4:

Multivariate Cox Regression Analysis for Overall Survival Over Entire Cohort

Variable Hazard Ratio 95% CI (Lower) 95% CI (Upper) p-value
Age at Diagnosis
<50 1 Reference
≥50 1.045 0.627 1.743 0.865
Ethnicity
White 1 Reference
Black 0.790 0.372 1.677 0.540
Hispanic 1.035 0.657 1.632 0.881
Asian/Indian 0.501 0.179 1.405 0.501
KPS
≥70 1 Reference
<70 3.702 1.608 8.520 0.002
Extent of Surgical Resection
Gross Total Resection 1 Reference
Subtotal Resection 1.532 0.992 2.366 0.054
Biopsy 2.209 1.129 4.320 0.021
RPA Class
III 1 Reference
IV 3.178 1.223 8.255 0.018
V/VI 3.499 0.979 12.508 0.054
RT Technique
IMRT 1 Reference
3D CRT 0.618 0.363 1.055 0.078
2D 2.261 0.278 18.402 0.446
RT Total Dose
<36 Gy 3.978 1.836 8.621 0.001
36–54 Gy 1.214 0.651 2.264 0.542
>54 Gy 1 Reference
Laterality
Unilateral 1 Reference
Bilateral 1.468 0.908 2.372 0.117
Multicentricity
No 1 Reference
Yes 1.130 0.736 1.735 0.576
Temozolomide
Yes 1 Reference
No 3.908 1.526 10.008 0.004