Table 1.
Characteristics of the Participants at Baseline.*
| Characteristic | Invasive Strategy (N = 347) | Conservative Strategy (N = 358) |
|---|---|---|
| Age — yr | 62.1±10.4 | 63.3±11.2 |
| Male sex — no. (%) | 235 (67.7) | 243 (67.9) |
| White race — no./total no. (%)† | 235/336 (69.9) | 230/343 (67.1) |
| Hypertension — no. (%) | 320 (92.2) | 336 (93.9) |
| Diabetes — no. (%) | 192 (55.3) | 193 (53.9) |
| Previous myocardial infarction — no. (%) | 57 (16.4) | 67 (18.7) |
| New-onset angina during previous 3 mo — no./total no. (%) | 50/335 (14.9) | 61/342 (17.8) |
| History of heart failure — no. (%) | 180 (51.9) | 192 (53.6) |
| Previous cerebrovascular disease — no. (%) | 46 (13.3) | 49 (13.7) |
| History of peripheral artery disease — no. (%) | 25 (7.2) | 23 (6.4) |
| Receipt of dialysis — no. (%) | 180 (51.9) | 206 (57.5) |
| Creatinine level at randomization — mg/dl‡ | 3.3±1.5 | 2.9±1.0 |
| Estimated glomerular filtration rate at randomization — ml/min‡ | 22.5±8.8 | 24.1±8.2 |
| Degree of ischemia on stress test — no./total no. (%) | ||
| Moderate | 218/342 (63.7) | 225/356 (63.2) |
| Severe | 124/342 (36.3) | 131/356 (36.8) |
| SAQ score§ | ||
| Summary score | 76.0±19.9 | 76.7±18.5 |
| Physical Limitation score | 75.0±25.8 | 75.1±24.3 |
| Quality of Life score | 65.8±28.2 | 67.1±26.9 |
| Angina Frequency score | 87.0±17.8 | 87.6±17.0 |
| Angina frequency — % | ||
| Daily or weekly | 11.9 | 11.7 |
| Monthly | 38.2 | 40.2 |
| None | 50.0 | 48.0 |
| Score on Rose Dyspnea Scale¶ | 1.5±1.5 | 1.5±1.4 |
| Score on EQ-5D visual analogue scale‖ | 60.3±18.1 | 61.7±17.4 |
*
Plus–minus values are means ±SD.
†
Race was reported by the participant.
‡
These data do not include participants who were receiving dialysis.
§
On the Seattle Angina Questionnaire (SAQ), the Summary score is an average of the Physical Limitation, Quality of Life, and Angina Frequency scores; SAQ scores range from 0 to 100, with higher scores indicating better health status.
¶
On the Rose Dyspnea Scale, scores range from 0 to 4, with higher scores indicating shortness of breath with milder activities.
‖
On the European Quality of Life–5 Dimensions (EQ-5D) visual analogue scale, scores range from 0 to 100, with higher scores indicating better health status.