Table 2.

Logistic regression analyses of components in IGFs/IGF-IR system in relation to the sensitivity to IGF-IR inhibitor BMS-536924

Gene	P	Odds ratio* (95% CI)	AUC
IGF-I	0.039	2.86 (0.08–0.96)	0.67
IGF-II	0.062	2.27 (0.13–1.04)	0.63
IGF-I + IGF-II	0.0004	4.76 (0.07–0.62)	0.87
IGF-IR	0.011	3.45 (0.07–0.78)	0.8
IGFBP-3	0.006	0.27 (1.39–14.58)	0.75
IGFBP-6	6.79E–06	0.07 (3.45–150.88)	0.91
Insulin	0.556	1.26 (0.58–2.98)	0.53
IR	0.1094	1.94 (0.87–5.08)	0.75

Abbreviations: 95% CI, 95% confidence interval; AUC, area under the receiver operating characteristic curve; IR, insulin receptor.

^*For odds of BMS-536924–sensitive versus resistant cell line groups, as defined in Table 1.