. Author manuscript; available in PMC: 2021 May 1.

Published in final edited form as: Biol Blood Marrow Transplant. 2019 Dec 9;26(5):943–948. doi: 10.1016/j.bbmt.2019.12.002

Table 3.

Univariate analysis of pulmonary function test parameters as risk factors for development of bronchiolitis obliterans syndrome (Odds ratio for each 20% decrease relative to 100% predicted.)

Pre-HCT Parameter	Odds Ratio	95% CI	P-value
FEV₁	1.14	0.98–1.31	0.09
FEF_25–75	1.13	1.03–1.24	0.01
FVC	1.05	0.91–1.22	0.51
TLC	0.92	0.78–1.10	0.36
DLCO	0.94	0.80–1.10	0.43
Day 80 Parameter
FEV₁	1.27	1.06–1.52	0.008
FEF_25–75	1.20	1.08–1.34	<0.001
FVC	1.14	0.95–1.36	0.17
TLC	0.98	0.82–1.16	0.78
DLCO	0.94	0.79–1.12	0.47

Abbreviations. FEV₁: forced expiratory volume in 1 second; FEF_25–75: forced expiratory flow between 25–75% maximum; FVC: forced vital capacity; TLC: total lung capacity; DLCO: diffusing capacity of the lungs for carbon monoxide.