Table 2.

Systemic surveillance of CF toxicity

	CF			saline			CF			saline
	creatinine (mg/dl)						blood urea nitrogen (BUN, mg/dl)
days after injection	mean	SD	number	mean	SD	number	mean	SD	number	mean	SD	number
0	0.52	0.06	10	0.58	0.04	6	10.1	2.6	10	10.8	2.8	6
1	0.57	0.05	7	0.55	0.06	4	13.3	2.9	7	10.0	1.2	4
2	0.54	0.05	7	0.55	0.06	4	10.9	1.7	7	10.0	0.8	4
7	0.55	0.06	4	0.60	0.00	3	10.0	0.0	4	11.7	2.5	3
28	0.67	0.06	3	0.70	0.00	3	12.3	1.2	3	10.0	1.0	3
	AST (U/L)						ALT (U/L)
0	32.9	31.3	10	20.3	7.9	6	30.6	7.3	10	27.5	7.5	6
1	17.1	14.5	7	13.3	4.0	4	35.1	12.1	7	31.5	5.1	4
2	19.9	13.4	7	26.3	13.2	4	23.6	4.9	7	31.3	6.3	4
7	17.0	5.8	4	20.7	3.5	3	19.5	2.4	4	22.3	8.6	3
28	23.7	10.8	3	24.0	9.5	3	24.7	2.5	3	33.3	9.5	3
	iron (U/L)						anion gap (Meq/L)
0	191.8	40.2	10	211.8	26.0	6	16.1	2.2	10	16.2	1.6	6
1	109.3	84.0	7	222.5	13.0	4	16.3	1.8	7	15.3	1.5	4
2	218.0	40.3	7	226.5	14.4	4	13.1	2.3	7	12.0	2.9	4
7	242.3	47.6	4	242.3	26.4	3	18.0	2.7	4	14.3	4.9	3
28	217.7	14.0	3	178.7	51.4	3	12.0	4.4	3	13.0	1.0	3
	white blood cell (k/mcl)						platelets (k/mcl)
0	5.9	0.9	10	6.5	1.4	6	189.9	44.6	10	238.7	32.9	6
1	8.8	1.9	7	5.4	0.9	3	159.3	21.9	7	276.0	90.7	3
2	11.4	1.0	6	4.0	1.2	4	272.0	53.5	6	300.5	98.5	4
7	6.8	0.8	4	5.8	2.0	3	233.8	79.9	4	237.7	30.9	3
28	2.3	1.5	3	3.6	1.8	3	238.0	37.2	3	261.7	66.5	3

^***The bolded values were statistically significantly different, iron day 1, p=0.001; WBC day 1, p=0.003, day 2, p<0.001; platelets day 1, p=0.02