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Simplified model for interactions between the frontal cortex and bed nucleus of the stria terminalis (BNST). Excitatory neurons in the infralimbic cortex project to the BNST, which plays an important role in driving anxiety-related behaviors. In contrast the prelimbic cortex exerts inhibitory input on the amygdala, which in turn may reduce anxiety-related behaviors. Mouse drawings by Natalia Duque-Wilckens.
