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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Arthritis Rheumatol. 2020 Apr 30;72(6):1026–1035. doi: 10.1002/art.41214

Table 1.

Unweighted ANA counts, sample sizes, and category percentages for selected characteristics by time period.

Period 1: 1988-1991
Period 2: 1999-2004
Period 3: 2011-2012
Combined
No. of Participants: No. of Participants: No. of Participants: No. of Participants:
Characteristic a ANA+ Total (%) ANA+ Total (%) ANA+ Total (%) ANA+ Total (%)
Overall 643 4,727 (100) 580 4,749 (100) 753 4,735 (100) 1,976 14,211 (100)
Sex
 Male 216 2,363 (50.0) 169 2,282 (48.1) 265 2,338 (49.4) 650 6,983 (49.1)
 Female 427 2,364 (50.0) 411 2,467 (52.0) 488 2,397 (50.6) 1,326 7,228 (50.9)
Age (years)
 Adolescent (12-19) 45 676 (14.3) 114 1,190 (25.1) 102 843 (17.8) 261 2,709 (19.1)
 Younger Adult (20-49) 248 2,218 (46.9) 188 1,905 (40.1) 275 2,080 (43.9) 711 6,203 (43.7)
 Older Adult ( ≥ 50 ) 350 1,833 (38.8) 278 1,654 (34.8) 376 1,812 (38.3) 1,004 5,299 (37.3)
Race/Ethnicity
 Non-Hispanic White 252 2,060 (43.6) 248 2,115 (44.5) 269 1,669 (35.3) 769 5,844 (41.1)
 Non-Hispanic Black 176 1,164 (24.6) 137 993 (20.9) 223 1,219 (25.7) 536 3,376 (23.8)
 Mexican-American 196 1,354 (28.6) 156 1,245 (26.2) 69 543 (11.5) 421 3,142 (22.1)
 Other 19 149 ( 3.2) 39 396 ( 8.3) 192 1,304 (27.5) 250 1,849 (13.0)
Body Mass Index (BMI)
 Underweight/Healthy 293 2,191 (46.5) 238 1,880 (39.7) 249 1,729 (37.1) 780 5,800 (41.1)
 Overweight 197 1,483 (31.5) 160 1,462 (30.9) 224 1,361 (29.2) 581 4,306 (30.5)
 Obese 150 1,036 (22.0) 181 1,393 (29.4) 264 1,571 (33.7) 595 4,000 (28.4)
Smoking Exposure
 None 88 411 ( 9.1) 274 1,929 (40.9) 446 2,612 (55.2) 808 4,952 (35.4)
 Second-Hand 352 2,788 (61.6) 212 1,752 (37.1) 166 1,154 (24.4) 730 5,694 (40.7)
 Active 164 1,326 (29.3) 92 1,039 (22.0) 140 967 (20.4) 396 3,332 (23.8)
Alcohol Consumption
 None 349 2,009 (53.0) 166 1,050 (35.4) 175 898 (29.3) 690 3,957 (40.3)
 Light 104 834 (22.0) 156 1,225 (41.3) 230 1,349 (44.0) 490 3,408 (34.7)
 Moderate/Heavy 93 948 (25.0) 49 695 (23.4) 110 818 (26.7) 252 2,461 (25.1)

Abbreviations: ANA = antinuclear antibodies; ANA+ = positive for ANA.

NOTE: Some groups were oversampled in certain cycles (e.g., adolescents in 1999-2004 and Asian-Americans in 2011-2012).

a

BMI was categorized as underweight/healthy, overweight, or obese using standard cut points of <25, 25 to <30, or ≥30 kg/m2 for persons ≥20 years old and by applying 2000 CDC growth chart percentiles of <85, 85 to <95, or ≥95 for persons 12-19 years old. Smoking exposure was based on current measured cotinine levels and classified as none (<0.05 ng/ml), second-hand (0.05 to 15 ng/ml), or active (>15 ng/ml). Alcohol consumption (available for ages ≥20 years) was based on the number of drinks in the past year and classified as none (<12 total), light (1-3 per week), or moderate/heavy (>3 per week).