Table 3:
iRBDA | DLBB | PDC | p <0.05 | |
---|---|---|---|---|
Sex (M/F) | 4/2 | 6/0 | 5/1 | |
Age at RBD Symptom Onset (yrs) | 57.7 + 8.5 | 60.2 + 7.8 | 68.0 + 5.8 | |
Age at RBD Diagnosis (yrs) | 62.7 + 8.6 | 68.3 + 3.4 | 70.3 + 5.1 | |
Duration RBD Symptoms to RBD Dx (yrs) | 4.5 + 2.9 | 7.4 + 4.6 | 2.3 + 2.0 | |
Age at 1st Autonomic Symptoms (yrs) | 62.8 + 4.5 | 65.3 + 6.9 | 68.3 + 4.5 | |
Age at Autonomic Testing (yrs) | 62.7 + 8.6 | 68.8 + 3.1 | 70.3 + 5.1 | |
Duration Autonomic Symptoms to ARS (yrs) | 2.1 + 1.7 | 3.8 + 3.4 | 0.4 + 0.5 | B>C |
Duration Autonomic Testing to Phenoconversion Dx (years) | NA | 5.3 + 3.4 | 5.5 + 5.2 | |
Total CASS Score | 2.8 + 1.7 | 4.0 + 2.0 | 1.7 + 1.0 | B>C |
Sudomotor CASS Score | 1.8 + 1.2 | 1.0 + 1.3 | 1.0 + 0.8 | |
Cardiovagal CASS Score | 0.3 + 0.8 | 1.2 + 0.8 | 0 + 0 | B>C |
Adrenergic CASS Score | 0.7 + 0.8 | 2.0 + 1.3 | 0.7 + 0.8 | |
% Anhidrosis* | 5.5 + 3.5 | 7.0 + 0 | 15.9 + 15.6 |
n=1 DLB, 2 iRBD, 3 PD patients
CASS=Composite autonomic severity score; RBD=REM sleep behavior disorder, PD=Parkinson’s disease; DLB=Dementia with Lewy bodies, Dx=diagnosis, ARS=autonomic reflex screen