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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Clin Auton Res. 2020 Mar 19;30(3):207–213. doi: 10.1007/s10286-020-00674-5

Table 3:

Comparison of Demographic and Autonomic Variables Between Phenoconversion Subgroups and Non-Phenoconverters

iRBDA DLBB PDC p <0.05
Sex (M/F) 4/2 6/0 5/1
Age at RBD Symptom Onset (yrs) 57.7 + 8.5 60.2 + 7.8 68.0 + 5.8
Age at RBD Diagnosis (yrs) 62.7 + 8.6 68.3 + 3.4 70.3 + 5.1
Duration RBD Symptoms to RBD Dx (yrs) 4.5 + 2.9 7.4 + 4.6 2.3 + 2.0
Age at 1st Autonomic Symptoms (yrs) 62.8 + 4.5 65.3 + 6.9 68.3 + 4.5
Age at Autonomic Testing (yrs) 62.7 + 8.6 68.8 + 3.1 70.3 + 5.1
Duration Autonomic Symptoms to ARS (yrs) 2.1 + 1.7 3.8 + 3.4 0.4 + 0.5 B>C
Duration Autonomic Testing to Phenoconversion Dx (years) NA 5.3 + 3.4 5.5 + 5.2
Total CASS Score 2.8 + 1.7 4.0 + 2.0 1.7 + 1.0 B>C
Sudomotor CASS Score 1.8 + 1.2 1.0 + 1.3 1.0 + 0.8
Cardiovagal CASS Score 0.3 + 0.8 1.2 + 0.8 0 + 0 B>C
Adrenergic CASS Score 0.7 + 0.8 2.0 + 1.3 0.7 + 0.8
% Anhidrosis* 5.5 + 3.5 7.0 + 0 15.9 + 15.6
*

n=1 DLB, 2 iRBD, 3 PD patients

CASS=Composite autonomic severity score; RBD=REM sleep behavior disorder, PD=Parkinson’s disease; DLB=Dementia with Lewy bodies, Dx=diagnosis, ARS=autonomic reflex screen