Table 2. Incidence of Colorectal Cancer in the Study Groups according to the Presence of CKD or Diabetes.

Group	Total	Incident case	Incidence* (95% CI)	IRR (95% CI)
All
Control	97698	1812	179.2 (170.9–187.4)	reference
CKD-/DM+	17700	398	223.3 (201.3–245.2)	1.2 (1.1–1.4)
CKD+/DM-	22643	549	234.3 (214.7–253.9)	1.3 (1.2–1.4)
CKD+/DM+	8506	244	285.4 (249.6–321.2)	1.6 (1.4–1.8)
Male
Control	53172	1163	212.5 (200.3–224.7)	reference
CKD-/DM+	9913	252	254.1 (222.7–285.5)	1.2 (1.0–1.4)
CKD+/DM-	12031	344	277.4 (248.1–306.7)	1.3 (1.2–1.5)
CKD+/DM+	4642	141	302.5 (252.6–352.4)	1.4 (1.2–1.7)
Female
Control	44526	649	139.8 (129.1–150.6)	reference
CKD-/DM+	7787	146	184.6 (154.6–214.5)	1.3 (1.1–1.6)
CKD+/DM-	10612	205	185.8 (160.4–211.2)	1.3 (1.1–1.6)
CKD+/DM+	3864	103	264.8 (213.7–315.9)	1.9 (1.5–2.3)

CI, confidence interval; CKD, chronic kidney disease; DM, diabetes mellitus; IRR, incidence rate ratio.

^*Incidence per 100000 person-years.