Table 4.
Influence of morphological hemodynamic and flow dynamics-related factors on length of ICU stay after TCPC
| Variables | Univariate model | Multivariate model | ||||
|---|---|---|---|---|---|---|
| p value | HR | 95% CI | p value | HR | 95% CI | |
| Morphological factors | ||||||
| DORV | 0.278 | 0.692 | 0.355–1.348 | |||
| Dextrocardia | 0.579 | 0.822 | 0.413–1.639 | |||
| Heterotaxy | 0.485 | 1.263 | 0.656–2.427 | |||
| Azygos continuation | 0.175 | 1.842 | 0.763–4.444 | |||
| TAPVD/PAPVD | 0.269 | 1.597 | 0.696–3.676 | |||
| CAVV | 0.671 | 1.147 | 0.609–2.160 | |||
| Dominant RV | 0.401 | 1.513 | 0.576–3.984 | |||
| Hemodynamic factors | ||||||
| PAP | 0.580 | 10.28 | 0.933–1.133 | |||
| LAP | 0.926 | 1.005 | 0.897–1.126 | |||
| SVP | 0.899 | 1.002 | 0.975–1.030 | |||
| EDP | 0.920 | 1.006 | 0.890–1.138 | |||
| AVVR pre-TCPC | 0.061 | 2.331 | 0.961–5.650 | 0.050 | 1.044 | 1.001–6.024 |
| APC | 0.217 | 1.587 | 0.763–3.300 | |||
| Pre-TCPC data | ||||||
| Age at TCPC | 0.097 | 1.106 | 0.982–1.245 | |||
| CPB time | 0.113 | 1.006 | 0.999–1.013 | |||
| Aortic cross-clamp | 0.137 | 1.642 | 0.854–3.155 | |||
| Aortic cross-clamp time | 0.073 | 1.019 | 0.998–1.041 | |||
| BCPS pathway size | ||||||
| Small central PA | 0.198 | 1.592 | 0.784–3.226 | |||
| Diameter of right SVC | 0.900 | 1.011 | 0.853–1.199 | |||
| Diameter of left SVC | 0.220 | 1.075 | 0.958–1.206 | |||
| Diameter of right PA | 0.757 | 0987 | 0.850–1.125 | |||
| Diameter of left PA | 0.593 | 1.090 | 0.924–1.148 | |||
| Diameter of central PA | 0.219 | 0.936 | 0.843–1.040 | |||
| Distance between SVCs | 0.077 | 1.044 | 0.995–1.094 | |||
| TCPC conduit diameter | 0.450 | 0.874 | 0.616–1.241 | |||
| BCPS flow dynamics | ||||||
| Right dominant SVC (right to left) | 0.405 | 0.758 | 0.395–1.456 | |||
| Left dominant SVC (left to right) | 0.405 | 1.319 | 0.687–2.533 | |||
| Discordant relationship between dominant SVC and IVC | 0.043 | 2.288 | 1.028–5.102 | 0.037 | 2.370 | 1.052–5.348 |
ICU intensive care unit, TCPC total cavopulmonary connection, HR hazard ratio, CI confidence interval, DORV double-outlet right ventricle, TAPVC total anomalous pulmonary venous connection, PAPVC partial anomalous pulmonary venous connection, CAVV common atrioventricular valve, RV right ventricle, PAP pulmonary arterial pressure, LAP left atrial pressure, SVP systemic ventricular pressure, EDP end diastolic pressure, AVVR atrioventricular valve regurgitation, APC aortopulmonary collaterals, CPB cardiopulmonary bypass, BCPS bidirectional cavopulmonary shunt, PA pulmonary artery, SVC superior vena cava
Bold indicates p < 0.05