Table 1.
EC50 values for wild-type receptors in the absence and presence of 10 µmol/L Cu2+
| Receptor | Agonist | EC50 in the absence of Cu2+ in µmol/La | EC50 in the presence of Cu2+ in µmol/La |
|---|---|---|---|
| OR2M3 wt | 3-Mercapto-2-methylpentan-1-ol | 0.45 ± 0.19 | 0.29 ± 0.10 |
| OR2W1 wt | 2-Phenylethanethiol | 37.81 ± 0.62 | 106.21 ± 0.93 |
| OR2W1 wt | 3-Mercaptohexyl acetate | 132.10 ± 20.86 | 120.78 ± 1.59 |
| OR2W1wt | Allyl phenyl acetate | 64.40 ± 3.58 | 55.15 ± 8.59 |
| OR1A1 wt | (R)-(-)-Carvone | 126.47 ± 34.07 | 159.03 ± 43.09 |
| OR1A1 wt | 2-Phenylethanethiol | 205.94 ± 21.53 | 73.06 ± 16.35 |
| OR1A1 wt | 3-Mercaptohexyl acetate | 404.65 ± 86.73 | 353.78 ± 113.08 |
| A2A/A2B | Adenosine | 471.75 ± 35.10 | 452.95 ± 38.26 |
| S1P4b | CYM50308 | 516.51 ± 74.57 | 343.76 ± 91.02 |
aMean ± SD (n = 3–5)
bEC50 in nmol/L