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. 2019 Aug 21;77(11):2157–2179. doi: 10.1007/s00018-019-03279-y

Table 1.

EC50 values for wild-type receptors in the absence and presence of 10 µmol/L Cu2+

Receptor Agonist EC50 in the absence of Cu2+ in µmol/La EC50 in the presence of Cu2+ in µmol/La
OR2M3 wt 3-Mercapto-2-methylpentan-1-ol 0.45 ± 0.19 0.29 ± 0.10
OR2W1 wt 2-Phenylethanethiol 37.81 ± 0.62 106.21 ± 0.93
OR2W1 wt 3-Mercaptohexyl acetate 132.10 ± 20.86 120.78 ± 1.59
OR2W1wt Allyl phenyl acetate 64.40 ± 3.58 55.15 ± 8.59
OR1A1 wt (R)-(-)-Carvone 126.47 ± 34.07 159.03 ± 43.09
OR1A1 wt 2-Phenylethanethiol 205.94 ± 21.53 73.06 ± 16.35
OR1A1 wt 3-Mercaptohexyl acetate 404.65 ± 86.73 353.78 ± 113.08
A2A/A2B Adenosine 471.75 ± 35.10 452.95 ± 38.26
S1P4b CYM50308 516.51 ± 74.57 343.76 ± 91.02

aMean ± SD (n = 3–5)

bEC50 in nmol/L