Table 1.

CCD and values of response variables (predicted and experimental) for preparation of thyme O/W nanoemulsions

Runs	Amount of saponin (g)	Amount of thyme oil (mL)	Particle size (nm)		PDI		Zeta potential (mV)
			Expa	Preb	Expa	Preb	Expa	Preb
1	0.719	0.287	283.6	259.6	0.601	0.598	− 24.9	− 25.5
2	1.250	0.500	121.5	127.4	0.575	0.596	− 20.6	− 19.8
3	1.780	0.287	356.2	352.5	0.583	0.559	− 10.1	− 9.5
4	1.250	0.500	112.2	127.4	0.601	0.596	− 19.8	− 19.8
5	1.250	0.500	148.7	127.4	0.612	0.596	− 19	− 19.8
6	1.250	0.800	492.8	587.8	0.721	0.765	− 21.4	− 20.7
7	2.000	0.500	479.5	512.6	0.683	0.723	− 13.6	− 14.1
8	1.250	0.200	245.3	245.1	0.414	0.421	− 16.9	− 16.9
9	1.780	0.712	678.6	607.5	0.771	0.721	− 17.1	− 16.4
10	1.250	0.500	127.5	127.4	0.596	0.596	− 19.8	− 19.8
11	1.250	0.500	127.4	127.4	0.596	0.596	− 19.8	− 19.8
12	0.719	0.712	580.5	489.2	0.952	0.923	− 17.9	− 19.0
13	0.500	0.500	301.6	363.3	0.881	0.892	− 24.8	− 23.7

^aExperimental values of studied responses

^bPredicted values of studied responses