Table 1.

Baseline parameters in each group

Variables	Placebo (n=42)	CLA (n=40)	P -Value
	Baseline	Baseline
Age Pack/year BMI FEV1 (%) FVC (%) FEV1/FVC ratio 6MWT mMRC BODE index IL-6 (pg/ml) SIRT1 (pg/ml)	61.55±10.81 45.71±26.11 24.84±3.06 40.27±15.09 56.69±17.77 57.13±8.66 335.79±190.89 2.36±0.54 4.05±1.92 4.05 (3.14-5.24) 15.30 (12-17.60)	63.82±10.58 43.40±25.11 25.46±3.85 46.14±17.80 65.93±18.84 56.29±9.86 397.92±141.50 2.58±0.54 4.22±1.88 3.83 (2.60-4.82) 11.75 (6.30-16.90)	0.338 0.684 0.426 0.111 0.049 0.684 0.099 0.084 0.675 0.489 0.100

BMI: body mass index, FEV1: Forced expiratory volume in 1 second, FVC: Forced vital capacity, BODE: (BMI, Airway obstruction, Dyspnea, Exercise tolerance)-index, 6MWT:  6-minute walk distance, mMRC: Modified Medical Research Council, BODE: (BMI, Airway obstruction, Dyspnea, Exercise tolerance) index, IL-6: interleukin-6, SIRT1: sirtuin 1.