Table 2.
NAb Titer (Pre-treatment) | Gene Copy Number/Cella | hFIX Plateau (ng/mL) | Inhibitor | |
---|---|---|---|---|
Group 1 (Early) | ||||
1001 | <1:3 | 3 | 96 | negative |
1002 | <1:3 | 0.48 | 0 | positive (0.5 BU) |
1003 | <1:3 | 0.75 | 89 (pre-inhibitor) | positive (5.5 BU) |
Group 2 (Delayed) | ||||
2001 | 1:3 | 0.66 | 5 | negative |
2102 | <1:3 | 0.25 | 25 | negative |
2003 | 1:3 | 0.19 | 215 | negative |
Week 16.