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. 2020 May 12;17:1129–1138. doi: 10.1016/j.omtm.2020.05.001

Table 2.

Summary of Results of Early versus Delayed ATG IS with AAV Vector Administration

NAb Titer (Pre-treatment) Gene Copy Number/Cella hFIX Plateau (ng/mL) Inhibitor
Group 1 (Early)
1001 <1:3 3 96 negative
1002 <1:3 0.48 0 positive (0.5 BU)
1003 <1:3 0.75 89 (pre-inhibitor) positive (5.5 BU)
Group 2 (Delayed)
2001 1:3 0.66 5 negative
2102 <1:3 0.25 25 negative
2003 1:3 0.19 215 negative
a

Week 16.