Figure 5.

Whole-Body MicroPET/CT Imaging Showing Increased ⁸⁹Zr-oxine-EPCs Accumulation in PAH Compared with Control Rats

Maximum intensity projections (MIPs) of representative rats are shown at five time points after intravenous injection. ⁸⁹Zr-oxine-EPCs were distributed primarily to the lung at 1 h and then migrated to the liver and spleen in both control and PAH rats. The accumulation of EPCs in the lungs of PAH rats was higher than that in healthy rats at different time points. The liver and spleen also showed moderate to considerable accumulation in both control and PAH groups (n = 4 rats per time point in each group).