Table 5.
The Three Selected C. glabrata Genome Sequences for Experimental Validation and Their Predicted Ability to Cross Lipid Bilayer by CPPpred
| ID | Sequence | Net Charge | Length | Deep-AmPEP30 | RF-AmPEP30 | ΔGa (kcal/mol) | Log Pcalc1 | Log Pcalc2 |
|---|---|---|---|---|---|---|---|---|
| P3 | FWELWKFLKSLWSIFPRRRP | +4 | 20 | 0.999090 | 0.785833 | −14.3 | −19.3 | −3.9 |
| P10 | ICTTLNWMVKLTCLTHVTLTTRWC | +2 | 24 | 0.998451 | 0.627500 | −12.8 | −5.5 | 3.1 |
| P26 | RWPPTTTLCYLSRPRRCSWTSSVCRCTLT | +7 | 29 | 0.999972 | 0.709167 | −9.2 | −31.7 | −13.4 |
Log Pcalc of membrane permeability coefficient predicted using the dragging optimization method (log Pcalc1) and the global optimization method (log Pcalc2).
a
Water-to-membrane transfer free energy by CPPpred..