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MTT assay was performed following different treatments. (A) Effect of cultured condition on NSCLC cell viability. A549 cells were maintained under normoxic or hypoxic condition for 12, 24, or 48 h; *P<0.05. (B) Effect of DHE on cell viability under normoxic or hypoxic condition. A549 cells were treated with different concentrations of DHE (10, 20, 40 μM) for 24 h and exposed to normoxic or hypoxic condition; *P<0.05.
