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. 2020 May 28;40(5):BSR20194284. doi: 10.1042/BSR20194284

Figure 6. Activation of Wnt/β-catenin pathway reversed the effects of DHE on EMT.

Figure 6

A549 cells were pretreated with LiCl (10 μM) for 2 h, followed by incubation with 20 μM of DHE for 24 h under hypoxic condition. (A) Western blotting analysis was performed to detect the expression levels of β-catenin, E-cadherin, and N-cadherin. (B–D) Quantification analysis of β-catenin, E-cadherin, and N-cadherin. (E and F) Cell migration and invasion were measured. *P<0.05 vs. A549 cells under normoxic condition. #P<0.05 vs. A549 cells under hypoxic condition. &P<0.05 vs. A549 cells treated with DHE+hypoxia.