Figure 2.

MRI regions selected for prediction of visual-verbal function decline. The following regions were selected for wavelet features: middle and inferior temporal gyrus right, insula right, lateral remainder occipital lobe right, thalamus left, corpus callosum, lateral ventricle excluding temporal horn left, lateral ventricle temporal horn right, third ventricle, anterior orbital gyrus right, bilateral inferior frontal gyrus, superior frontal gyrus right, lingual gyrus left, bilateral cuneus, bilateral medial orbital gyrus, posterior orbital gyrus left, bilateral substantia nigra, bilateral subgenual frontal cortex, bilateral subcallosal area, bilateral pre-subgenual frontal cortex, and bilateral superior temporal gyrus anterior part. For the combination with neuropsychology, the following regions were selected for wavelet features: anterior temporal lobe lateral part right, middle and inferior temporal gyrus right, insula left, middle frontal gyrus left, inferolateral remainder parietal lobe left, caudate nucleus left, lateral ventricle excluding temporal horn left, lateral ventricle temporal horn right, third ventricle, bilateral inferior and superior frontal gyrus, bilateral lingual gyrus, cuneus right, bilateral medial orbital gyrus, posterior orbital gyrus right, substantia nigra left, subgenual frontal cortex right, bilateral subcallosal area, bilateral pre-subgenual frontal cortex, and bilateral superior temporal gyrus anterior part.