Table 3.
Biochemical analysis of rabbits from RFG (n = 8) before the beginning of the treatment with fat diet and at the end of the 3-month fat diet.
| Baseline (n = 8) | After 3 months (n = 8) | t | P value | |
|---|---|---|---|---|
| Weight(kg) (NDG) | 0.96 ± 0.05 | 2.90 ± 0.08 | −73.655 | <0.001 |
| Weight (kg) (FDG) | 0.99 ± 0.08 | 2.98 ± 0.15 | −49.925 | <0.001 |
| Weight (kg) (RFG) | 1.01 ± 0.08 | 2.96 ± 0.07 | −39.000 | <0.001 |
| ALT (NDG) | 43.20 ± 9.65 | 44.81 ± 7.95 | −0.781 | 0.461 |
| ALT (FDG) | 41.22 ± 8.83 | 50.86 ± 24.53 | −1.172 | 0.280 |
| ALT (RFG) | 44.76 ± 12.80 | 61.06 ± 20.26 | −2.160 | 0.068 |
| AST (NDG) | 36.38 ± 8.61 | 40.51 ± 6.46 | −2.490 | 0.042 |
| AST (FDG) | 33.73 ± 5.91 | 84.32 ± 54.94 | −2.639 | 0.033 |
| AST (RFG) | 34.88 ± 4.98 | 77.91 ± 24.54 | −5.587 | 0.001 |
| CREA (NDG) | 67.94 ± 8.39 | 77.38 ± 10.45 | −7.002 | <0.001 |
| CREA (FDG) | 64.72 ± 6.27 | 111.92 ± 11.38 | −10.794 | <0.001 |
| CREA (RFG) | 65.75 ± 9.69 | 127.63 ± 10.84 | −12.390 | <0.001 |
| TG (NDG) | 0.63 ± 0.20 | 0.62 ± 0.21 | 0.086 | 0.934 |
| TG (FDG) | 0.50 ± 0.16 | 0.90 ± 0.42 | −2.230 | 0.061 |
| TG (RFG) | 0.48 ± 0.07 | 0.76 ± 0.28 | −2.986 | 0.020 |
| TC (NDG) | 1.94 ± 0.21 | 2.19 ± 0.30 | −2.919 | 0.022 |
| TC (FDG) | 1.88 ± 0.28 | 30.32 ± 5.74 | −14.078 | <0.001 |
| TC (RFG) | 1.99 ± 0.43 | 11.84 ± 2.78 | −9.275 | <0.001 |
| HDL (NDG) | 0.93 ± 0.19 | 1.03 ± 0.20 | −3.359 | 0.012 |
| HDL (FDG) | 0.94 ± 0.25 | 3.28 ± 1.61 | −3.815 | 0.007 |
| HDL (RFG) | 0.93 ± 0.17 | 1.58 ± 0.35 | −4.880 | 0.002 |
| LDL (NDG) | 0.84 ± 0.22 | 0.91 ± 0.22 | −1.270 | 0.245 |
| LDL (FDG) | 0.95 ± 0.12 | 16.45 ± 3.16 | −13.489 | <0.001 |
| LDL (RFG) | 0.80 ± 0.27 | 6.23 ± 1.53 | −9.221 | <0.001 |
| Lp-PLA2# (NDG) | 461.50 ± 89.57 | 520.14 ± 51.55 | −1.930 | 0.095 |
| Lp-PLA2# (FDG) | 525.48 ± 32.50 | 1928.88 ± 385.78 | −10.090 | <0.001 |
| Lp-PLA2# (RFG) | 494.88 ± 32.56 | 953.20 ± 96.66 | −12.816 | <0.001 |
#The test result of homogeneity of variance was P < 0.05, and Dunnett's T method was used for multiple comparison of P value correction, while the Bonferroni method was used for the other indicators. NDG, normal diet group; FDG, fat diet group; RFG, fat diet with resveratrol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CREA, creatinine; TG, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Lp-PLA2, lipoprotein-associated phospholipase A2.