Table II.

Significant values (p < 0.05) for the constants in model [7] for the different dependent variables in the first fed-batch culture.

Parameter	Biomass	Viable cell counts	Nisin	Lactic acid	Acetic acid	Butane-2,3-diol
A1	4.12 ± 0.631	1.86 ± 0.084	1.13 ± 0.113	5.71 ± 0.235	1.16 ± 0.003	2.75 ± 0.277
A2	−3.60 ± 0.545	−1.56 ± 0.072	8.67 ± 0.4244	−4.04 ± 0.225	−0.70 ± 0.012	−2.00 ± 0.265
A3	0.83 ± 0.116	0.41 ± 0.015	−2.07 ± 0.206	0.88 ± 0.054	0.12 ± 0.005	0.37 ± 0.064
A4	−1.09 ± 0.383	−0.15 ± 0.051	−9.25 ± 1.547	−0.92 ± 0.040	−0.46 ± 0.021	−0.19 ± 0.021
A5	0.14 ± 0.062	0.03 ± 0.008	2.93 ± 0.314	0.26 ± 0.019	0.15 ± 0.011	0.03 ± 0.003
A6	0.35 ± 0.168	NS	0.74 ± 0.203	NS	NS	NS
R2	0.9950	0.9948	0.9993	0.9986	0.9949	0.9954
RPDM (%)	3.335	0.228	1.121	3.760	1.701	5.809
VpHopt	1.81	1.92	2.32	2.30	2.83	2.40
pHopt = 7.0 – VpHopt	5.19	5.08	4.68	4.70	4.17	4.60
Gopt (g/l)	1.64	2.72	1.29	1.76	1.41	2.80