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. 2020 Apr 24;6(5):613–615. doi: 10.1021/acscentsci.0c00303

Figure 1.

Figure 1

(A) Schematic illustration of X-ray-induced PDT with PLGA-TPP nanocarriers consisting of PLGA, verteporfin (VP), gold nanoparticles, and a mitochondria-targeting ligand. (B) Scanning electron microphotograph of the PLGA nanocarriers, inset is transmission electron microphotograph of the same sample at higher magnification. (C) A Kaplan–Meier curve demonstrating the extended survival in mice with colorectal tumors treated with X-ray-induced PDT and PLGA-TPP nanoconstructs (4Gy and PLGA-TPP). Black arrow indicates the time of treatment administration. Reproduced from ref (3). Copyright 2020, American Chemical Society.