Table 1.
Cohort | SLE high | SLE low | HC |
---|---|---|---|
Individuals, no. | 92 | 92 | 100 |
Age (median, range) | 42 (14–73) | 44 (19–81) | 49 (16–81) |
Disease duration (median, range) | 4 (0–40) | 8 (0–43) | N/A |
Gender (% female) | 89 | 89 | 85 |
Ethnicity (% white) | 90 | 90 | 90 |
SLEDAI (median, range) | 8 (2–28) | 2 (0–12) | N/A |
Active nephritis1 (%) | 31 | 1 | N/A |
Nephritis ever (%) | 43 | 43 | N/A |
class I (%) | 0 | 0 | N/A |
class II (%) | 0 | 0 | N/A |
class III (%) | 6 | 6 | N/A |
class IV (%) | 76 | 76 | N/A |
class V (%) | 18 | 18 | N/A |
Anti-C1q antibodies current (%) | 27 | 24 | N/A |
Immunosuppressive treatment (%) | 40 | 50 | N/A |
Azathioprine (%) | 25 | 25 | N/A |
CellCept (%) | 18 | 17 | N/A |
Methotrexate (%) | 2 | 0 | N/A |
Rituximab (%) | 0 | 0 | N/A |
Cyclosporine (%) | 9 | 9 | N/A |
Prednisone treatment (%) | 68 | 68 | N/A |
Prednisone dose (median, range) | 10 (0–40) | 10 (0–40) | N/A |
Hydroxychloroquine (%) | 30 | 37 | N/A |
1Defined as new onset of urinary casts, hematuria, pyuria and/or proteinuria according to SLEDAI-2 K [11]