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. 2020 May 29;22:126. doi: 10.1186/s13075-020-02221-z

Table 1.

Patient characteristics

Cohort SLE high SLE low HC
Individuals, no. 92 92 100
Age (median, range) 42 (14–73) 44 (19–81) 49 (16–81)
Disease duration (median, range) 4 (0–40) 8 (0–43) N/A
Gender (% female) 89 89 85
Ethnicity (% white) 90 90 90
SLEDAI (median, range) 8 (2–28) 2 (0–12) N/A
Active nephritis1 (%) 31 1 N/A
Nephritis ever (%) 43 43 N/A
class I (%) 0 0 N/A
class II (%) 0 0 N/A
class III (%) 6 6 N/A
class IV (%) 76 76 N/A
class V (%) 18 18 N/A
Anti-C1q antibodies current (%) 27 24 N/A
Immunosuppressive treatment (%) 40 50 N/A
 Azathioprine (%) 25 25 N/A
 CellCept (%) 18 17 N/A
 Methotrexate (%) 2 0 N/A
 Rituximab (%) 0 0 N/A
 Cyclosporine (%) 9 9 N/A
Prednisone treatment (%) 68 68 N/A
Prednisone dose (median, range) 10 (0–40) 10 (0–40) N/A
Hydroxychloroquine (%) 30 37 N/A

1Defined as new onset of urinary casts, hematuria, pyuria and/or proteinuria according to SLEDAI-2 K [11]