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. Author manuscript; available in PMC: 2020 May 29.
Published in final edited form as: Prostate. 2018 Apr 22;78(11):801–811. doi: 10.1002/pros.23537

FIGURE 1.

FIGURE 1

Comparison of Annexin (ANX2), Heat Shock Protein 60 (HSP60), and SPINK1/TATI expression in normal prostate, low grade prostate carcinoma (LGPCA) (Gleason score 6, Grade I), and high grade prostate carcinoma (HGPCA) (Gleason score 10, Grade V). Normal prostate with presence of the basal layer (A). Low grade PCA with well-defined microacinar glands demonstrating absence of basal layer and perineural involvement (B). High grade PCA with sheets of individual cells (C). ANX2 is expressed in the normal prostate glands (D) but not expressed in LGPCA (E) or HGPCA (F). HSP60 is expressed in normal glands (G) and shows patchy expression in LGPCA (H) and increased strong expression in HGPCA (I). SPINK1/TATI is not expressed in normal glands (J) but shows diffuse cytoplasmic expression in LGPCA (K) and patchy strong dot-like expression in HGPCA (L). Each slide is presented at 20× magnification. [Color figure can be viewed at wileyonlinelibrary.com]