Fig. 6.

Differential metabolic profiling in FMT_HC, FMT_MM, and PBS mice. a, b The concentrations of BM l-glutamic acid (a) and l-glutamine (b) in FMT_HC, FMT_MM, PBS, and normal mice. P value was calculated by two-tailed unpaired t test. c, d The concentrations of serum l-glutamic acid (c) and l-glutamine (d) in FMT_HC, FMT_MM, PBS, and normal mice. P value was calculated by two-tailed unpaired t test. e, f The concentrations of cecal l-glutamic acid (e) and l-glutamine (f) in FMT_HC, FMT_MM, PBS, and normal mice. P value was calculated by two-tailed unpaired t test. g, h The concentrations of serum urea (g) and NH₄⁺ (h) in FMT_HC, FMT_MM, and PBS mice, respectively. P value was determined by using two-way ANOVA test. i, j The deposition of monoclonal protein (lgG2b kappa) in the kidney surface of FMT_HC, FMT_MM, PBS, and normal mice. P value was determined by using one-tailed t test. k, l The concentrations of cecal urea after microbial cells being unbroken (k) and broken (l), respectively. P value was calculated using two-tailed unpaired t test. m, n The concentrations of cecal NH₄⁺ after microbial cells being unbroken (m) and broken (n), respectively. P value was calculated using two-tailed unpaired t test. o, p The activities of cecal urease (o) and glutamine synthase (p) in FMT_HC, FMT_MM, and PBS mice, respectively. P value was calculated by using two-tailed unpaired t test. q Scatter plot of enzyme activities in cecal contents of FMT_HC, FMT_MM, and PBS mice. *P < 0.05, **P < 0.01, ***P < 0.001