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. 2020 May 27;11:2041731420922701. doi: 10.1177/2041731420922701

Figure 5.

Figure 5.

Effect of LA and A-LA on modulation of cytokines and cartilage-related proteins in human OA cartilage explants. Cartilage explants were stimulated for 14 days, supernatants collected and protein concentrations were determined by Luminex technology. (a) IL-8, (b) IL-1β, (c) MMP-13, (d) TNF-α, (e) TIMP-1 and (f) aggrecan. Results are shown as mean ± SEM of triplicate determinations per sample (n = 6). *p ⩽ 0.05, **p ⩽ 0.01, *p ⩽ 0.001 versus control media.