Table 3.
Female controls n = 14 |
Female T2D patients n = 67 |
Male controls n = 16 |
Male T2D patients n = 62 |
p value | |
---|---|---|---|---|---|
LV end-diastolic volume indexed to BSA, ml/m2 | 81 ± 13 | 73 ± 12 | 93 ± 19** | 78 ± 12 | <0.0001 |
LV mass index, g/m2 | 41 ± 6 | 43 ± 7 | 51 ± 14*** | 52 ± 8† | <0.0001 |
LV mass to LV end-diastolic volume, g/ml | 0.50 ± 0.10 | 0.60 ± 0.11* | 0.56 ± 0.11*** | 0.67 ± 0.13**,† | <0.0001 |
LV ejection fraction, % | 60 ± 6 | 63 ± 7 | 59 ± 6 | 60 ± 6 | NS |
LA biplane end-systolic volumes, ml/m2 | 71 ± 16 | 70 ± 19 | 63 ± 16 | 72 ± 21 | NS |
Biplane LAEF, % | 59 ± 10 | 59 ± 7 | 60 ± 8** | 55 ± 6† | 0.0094 |
Peak systolic circumferential strain, negative (–), % | 23.5 ± 1.8 | 22.7 ± 2.8 | 19.1 ± 2.6*** | 20.5 ± 2.6† | <0.0001 |
Peak circumferential diastolic strain rate, s–1 | 1.41 ± 0.48 | 1.53 ± 0.31 | 1.26 ± 0.35 | 1.31 ± 0.35† | 0.0005 |
Values are mean ± SD or percentages.
BSA, body surface area; CMR, cardiac magnetic resonance; LAEF, left atrial ejection fractions; LV, left ventricular; SD, standard deviation; T2D, type 2 diabetes.
p < 0.05 female T2D versus female controls, with Bonferroni Correction.
p < 0.05 female T2D versus male T2D, with Bonferroni Correction.
p < 0.05 male T2D versus male controls, with Bonferroni Correction.
p < 0.05 male versus female controls, with Bonferroni Correction.