Table II.
Prognostic genes.
| Gene symbol | Name | Univariate HR (95% CI) | Coefficient | P-value | LASSO HR (95% CI) |
|---|---|---|---|---|---|
| TMEM45B | Transmembrane protein 45B | 0.899 (0.822-0.982) | -0.086 | 1.88x10-2 | 0.918 (0.864-0.975) |
| CDKN1B | Cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.928 (0.886-0.972) | -0.029 | 1.55x10-3 | 0.971 (0.914-1.032) |
| PKHD1L1 | Polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 | 0.938 (0.886-0.993) | -0.010 | 2.73x10-2 | 0.990 (0.932-1.052) |
| PLCL2 | Phospholipase C-like 2 | 0.961 (0.929-0.994) | -0.006 | 2.14x10-2 | 0.994 (0.936-1.056) |
| CKMT1A | Creatine kinase, mitochondrial 1A | 1.024 (1.000-1.049) | 0.001 | 4.90x10-2 | 1.001 (0.942-1.063) |
| SPINK5 | Serine peptidase inhibitor, Kazal type 5 | 1.027 (1.002-1.052) | 0.007 | 3.31x10-2 | 1.008 (0.948-1.070) |
| CST6 | Cystatin E/M | 1.027 (1.000-1.054) | 0.011 | 4.67x10-2 | 1.011 (0.952-1.074) |
| FABP5 | Fatty acid binding protein 5 (psoriasis-associated) | 1.037 (1.007-1.067) | 0.007 | 1.53x10-2 | 1.007 (0.948-1.070) |
| PTK6 | Protein tyrosine kinase 6 | 1.047 (1.010-1.084) | 0.029 | 1.11x10-2 | 1.030 (0.969-1.094) |
| TXNDC17 | Thioredoxin domain containing 17 | 1.047 (1.002-1.095) | 0.004 | 4.02x10-2 | 1.004 (0.945-1.066) |
| LTB4R | Leukotriene B4 receptor | 1.050 (1.007-1.096) | 0.018 | 2.39x10-2 | 1.018 (0.958-1.082) |
| FAM100A | Family with sequence similarity 100, member A | 1.050 (1.008-1.094) | 0.015 | 1.90x10-2 | 1.016 (0.956-1.079) |
| KRT10 | keratin 10 | 1.057 (1.025-1.091) | 0.016 | 4.33x10-4 | 1.016 (0.956-1.080) |
| PPP1R13L | Protein phosphatase 1, regulatory subunit 13 like | 1.059 (1.010-1.109) | 0.000 | 1.65x10-2 | 1.000 (0.941-1.063) |
| DLX3 | Distal-less homeobox 3 | 1.063 (1.025-1.102) | 0.008 | 9.40x10-4 | 1.008 (0.949-1.071) |
| KPRP | Keratinocyte proline rich protein | 1.064 (1.015-1.115) | 0.044 | 9.68x10-3 | 1.045 (0.984-1.111) |
| VSIG10L | V-set and immunoglobulin domain containing 10 like | 1.066 (1.011-1.123) | 0.021 | 1.87x10-2 | 1.021 (0.961-1.085) |
| MYOM3 | Myomesin 3 | 1.073 (1.015-1.134) | 0.040 | 1.25x10-2 | 1.041 (0.979-1.106) |
| NMU | Neuromedin U receptor 1 | 1.092 (1.042-1.144) | 0.072 | 2.22x10-4 | 1.075 (1.012-1.142) |
| PIGW | Phosphatidylinositol glycan anchor biosynthesis, class W | 1.113 (1.044-1.188) | 0.002 | 1.08x10-3 | 1.002 (0.943-1.064) |
HR, hazard ratio; CI, confidence interval.