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. Author manuscript; available in PMC: 2020 Dec 15.
Published in final edited form as: Am J Cardiol. 2019 Dec 15;124(Suppl 1):S28–S35. doi: 10.1016/j.amjcard.2019.10.027

Figure 4.

Figure 4

Immediate effects of phlorizin on macula densa delivery of Na, Cl, fluid volume, and SNGFR measured downstream of the macula densa to allow TGF to operate. Phlorizin was delivered to Bowman’s space.33 Cl = chloride; MD = macula densa; Na = sodium; SNGFRd = single-nephron glomerular filtration rate, determined by distal tubular collection; TGF = tubuloglomerular feedback; VED = early distal tubular flow rate. Data from Vallon V et al. Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption. J Am Soc Nephrol. 1999;10:2569–76.