Table 1.
Age, body mass index, and hormonal profile of the two studied groups
| Variable | PCOS women (study group) (n = 119) |
Non-PCOS controls (n = 118) |
p-value (95% CI) |
|---|---|---|---|
| Age (years) | 24.2 ±3.6 | 26.3 ±5.4 | 0.9 (–3.3, –2.1, –0.9) |
| BMI (kg/m<sup>2</sup>) | 30.7 ±6.0 | 24.5 ±4.5 | 0.001* (4.8, 6.2, 7.6) |
| FSH (mIU/ml) | 6.5 ±4.6 | 5.3 ±4.3 | 0.2 (0.06, 1.2, 2.3) |
| LH (mIU/ml) | 18.7 ±7.5 | 5.9 ±6.2 | 0.02* (11, 12.8, 14.6) |
| LH/FSH ratio | 2.8 ±3.3 | 1.1 ±2.7 | 0.01* (0.9, 1.7, 2.5) |
| Total testosterone (ng/dl) | 92.5 ±9.1 | 44.3 ±6.9 | 0.001* (46.1, 48.2, 50.3) |
| Free testosterone (pg/ml) | 5.7 ±3.6 | 2.5 ±2.8 | 0.003* (2.4, 3.2, 4.03) |
| Androstenedione (ng/ml) | 4.2 ±2.9 | 2.3 ±2.4 | 0.02* (1.22, 1.9, 2.58) |
| DHEA (ng/l) | 8937 ±2.9 | 5491 ±3.7 | 0.99 (3445.1, 345, 3446.9) |
BMI – body mass index, FSH – follicle stimulating hormone, LH – luteinising hormone, DHEA – dehydroepiandrosterone (normal 1330-7780 ng/l), PCOS – polycystic ovary syndrome, CI – confidence interval. Total testosterone normal value 6-86 ng/dl, free testosterone normal value 0.7-3.6 pg/ml, androstenedione normal value 0.7-3.1 ng/ml. Student’s t-test used for statistical analysis. * Significant difference. Data presented as mean ±standard deviation (SD)